Cornerback Lardarius Webb left practice early Friday afternoon and did not return.
Webb jogged off the field without any assistance and did not seem to be favoring anything.
Head Coach John Harbaugh said he did not have an update on the injury immediately after practice.
"[It was] nothing serious," he said.
Secondary/Assistant Head Coach Steve Spagnuolo said Webb got "dinged a little."
Webb suffered season-ending knee injuries in 2009 and 2012. He returned last year to start all 16 games and made 74 tackles, two interceptions and 22 pass deflections. Webb played especially well during the second half of the season and is looking to reach Pro Bowl form this year.
"I love Lardarius," Harbaugh said. "He cares. It matters to him. He wants to be great. He's faced some adversity with the hip flexors and all that, and that's a tough injury to come back from.
"He's fighting through it like crazy. He's going to be fine. It just takes time and you have to work through it. I love him, I love his passion, the way he works, [and] of course I love his talent. He's a good person; he's a good dad. I'm really proud of what he's done the last few years."
Chykie Brown stepped into Webb's starting position outside and Asa Jackson went into the slot.
Brown had another tough day, as he's frequently in good position but hasn't been making plays on the ball. Jackson showed his hops with a leaping pass deflection in the end zone during red-zone drills.
Here are some other highlights from practice:
- Head Coach John Harbaugh was asked whether Ray Rice will appeal his suspension. "I do not, and if I did, I wouldn't tell you," he said.
- Outside linebacker Elvis Dumervil visibly can't wait to strap on the pads. He ran over tight end Owen Daniels with one pass rush and Daniels got up with his arms out wide as if to say, "What the heck?!"
- While first-round pick C.J. Mosley is getting a lot of attention, don't forget about second-round defensive tackle Timmy Jernigan. He has explosion off the line and knifed through a guard and center with a swim move to get at Tyrod Taylor. It would have been a sack in a game.
- Back-to-back false starts by rookie tight end Crockett Gillmore and left guard Kelechi Osemele did not make Offensive Coordinator Gary Kubiak or quarterback Joe Flacco too happy. After the second one, Flacco yelled out, "C'mon guys!" It wasn't the cussing Terrell Suggs mentioned a couple days ago, but it's Flacco's way of reprimanding players.
- It was good to see running back Ray Rice playing around with fans on the sideline. Rice was joking with some children like he has in years past, taking pretend falls and tumbling down a hill.
- The defense owned a fourth-down drill. There were five snaps in a fourth-and-3 situation, and the defense won four of them. The offense had a pair of drops from wide receiver Marlon Brown and wide receiver Mike Willie.
- Brown atoned for the drop later on in practice when he dove to catch a long bomb down the sideline just short of the end zone.
- Undrafted rookie wide receiver Jeremy Butler continues to make plays. He made a nice catch diving to the ground for a long first down.
- Right tackle Jah Reid's athleticism was on display during a screen. The pass went to Daniels, who isn't as fast as he once was but still not slow. Reid went step-for-step with him down the field, paving the way for a long gain.
- The wide receivers have a fun new drill in which three players will stand around one that's about to catch a ball. As the pass comes in, the three other players swat around at it, simulating making a catch in traffic.
- Quote of the day goes to Steve Smith Sr., who had another strong practice: "I wanna stretch by osmosis."