C Tyler Linderbaum

Linderbaum is off to a strong start in his rookie career. Now he'll tangle with one of the bigger defensive linemen in the league in Dexter Lawrence, who tips the scales at 6-foot-4, 342 pounds. Lawrence is bigger than the Ravens' Travis Jones and leads the Giants with three sacks. It's a battle of first-round picks in the trenches that will help shape this game.

LB Patrick Queen

Queen is coming off his best game of the season in which he notched a game-changing interception. Now he'll have his hands full with Barkley, who is not only a premier runner but also a dangerous weapon as a receiver out of the backfield (18 catches for 143 yards).

OLB Jason Pierre-Paul

Pierre-Paul is going against the team he won a Super Bowl with during his eight seasons in New York. He'll go against left tackle Andrew Thomas, who has been the league's fifth-best pass protector, per Pro Football Focus. Thomas has yet to give up a sack this season and has surrendered just one QB hit. Pierre-Paul is only getting stronger with more time in the Ravens defense and had a sack and two pass breakups last week.

WR Devin Duvernay

It remains to be seen whether Rashod Bateman (foot) will play this week. If not, the Ravens are going to have to craft more ways to get Duvernay the ball. He could be especially important if Martindale calls for a heavy blitz, as Jackson will need a quick outlet that can do damage with the ball in his hands.

QB Lamar Jackson

Jackson is always a player to watch. But going against the Ravens' former defensive coordinator adds another wrinkle this week. Martindale knows what Jackson likes and doesn't like to see from opposing defenses. Jackson knows how Martindale likes to attack him, as he saw it in practice. Each will be trying to stay one step ahead of the other.