QB Lamar Jackson vs. LB Jeremiah Owusu-Koramoah

The Browns drafted Owusu-Koramoah in part because of his speed in the middle, knowing they face Jackson at least twice a year. He has often operated as a spy and could do so again. Owusu-Koramoah has turned into one of the game's better linebackers but will face a red-hot Jackson who is coming off a five-touchdown game and looks like the best quarterback in the league.

LT Ronnie Stanley vs. DE Myles Garrett

Stanley is back to his All-Pro form and has allowed zero sacks in 224 pass blocking snaps this season, according to Next Gen Stats. Last week, he allowed zero pressures against the Tampa Bay Buccaneers, but he has a tough matchup Sunday facing Garrett, the reigning Defensive Player of the Year.

ILB Roquan Smith vs. RB Nick Chubb

Chubb made his return from a serious knee injury last week and gives the Browns a bonafide runner who can swing a game, but he will face a stout Ravens defensive line with Smith behind it. Smith is coming off maybe his best game of the season where he posted 18 tackles, the second most in his career.

WR Rashod Bateman vs. CB Denzel Ward

Everything is starting to click for Bateman, who is fully healthy after dealing with injuries in the early years of his career. Bateman set a career-high with 121 yards last week and will face a strong cover corner in Ward, who has a league-leading 12 passes defended on the season.

S Kyle Hamilton vs. TE David Njoku

With Amari Cooper now on the Bills, Njoku might be Cleveland's new No. 1 target. Jameis Winston, who is making his first start of the season, will surely look Njoku's way Sunday. Hamilton has consistently delivered massive hits this season, so look for some sparks when he collides with Njoku, who is one of the league's most jacked tight ends.